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Author Level of evidence n Design Result Mandel347 I Hardcastle348 I Kronborg349 I Winawer350 I Kewenter351 I 46,551 152,850 61,933 21,756 21,347 initial and 19,991 follow-up Annual FOBT vs biennial FOBT vs usual care Biennial FOBT forx usual care Biennial FOBT vs usual care Annual FOBT plus rigid sigmoidoscopy vs annual rigid sigmoidoscopy alone FOBT initial evaluation and 1624 months Annual FOBT 33mortality, biennial no Biennial FOBT 15mortality Biennial FOBT 18mortality Annual FOBT 43mortality over rigid sigmoidoscopy alone Mortality pending but earlier stage tumors 34 Holbrook and Smith subcutaneous fat, body density, and visceral fat depots of males and females of different age groups.
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